夏江，博士。香港中文大学化学系及生命科学学院教授（终身教职）、博士生导师。1999年毕业于南京大学强化部获理学学士，2002年于南京大学获理学硕士学位，2006年毕业于美国斯坦福大学获得博士学位，在美国加州理工学院（兼聘霍华德休斯医学研究所）完成博士后训练后就职于香港中文大学化学系（2009-）。研究领域为化学生物学和合成生物学，研究课题包括 1) 新型生物交联反应及蛋白和抗体的官能化, 2) 基于蛋白质组装的合成代谢结和细胞器, 3) 外泌体改造及靶向递送， 以及在关节炎治疗和细菌感染中的应用。特别集中于人工细胞器的合成、功能和应用。目前在Biomaterials, ACS Chemical Biology, Molecular Pharmaceutics，JACS, PNAS, Bioconjugate Chemistry等期刊发表论超过100篇。

化学生物学；合成生物学；生物医学。

论文发表节选

1 Bao, Y.†; Xu, Z.†; Cheng, K.*; Li, X.; Chen, F.; Yuan, D.; Zhang, F.; Audrey Run-yu Che, A. R.-Y.; Zeng, X.; Zhao, Y.-D.*; Xia, J.*

Staudinger Reaction-Responsive Coacervates for Cytosolic Antibody Delivery and TRIM21-Mediated Protein Degradation.

J. Am. Chem. Soc. 2025, in press.

2 Kong, H.†; Xie, X.†; Bao, Y.; Zhang, F.; Bian, L.; Cheng, K*.; Zhao, Y.-D.*; Xia, J.*

Phase-separated spiropyran coacervates as dual-wavelength-switchable reactive oxygen generators.

Angew. Chem. Int. Ed. 2025, https://doi.org/10.1002/anie.202419538

3 Zhang, L.; Chen, Y.; Feng, D.; Xing, Z.; Wang, Y.; Bai, Y.; Shi, D.; Li, H.; Fan, X.; Xia, J.*; Wang, J.*

Recombinant Collagen Microneedles for Transdermal Delivery of Antibacterial Copper-DNA Nanoparticles to Treat Skin and Soft Tissue Infections.

J. Controll. Release 2025, in press.

4 Chen, H.;† Bao, Y;† Li, X.; Chen, F.; Sugimura, R.; Zeng, X.; Xia, J.*

Cell surface engineering by phase-separated coacervates for antibody display and targeted cancer cell therapy

Angew. Chem. Int. Ed. 2024, e202410566.

5 Li, B.; Yuan, D.; Chen, H.; Wang, X.; Liang, Y.; Wong, C.T.T.*; Xia, J.*

Site-Selective Antibody-Lipid Conjugates for Surface Functionalization of Red Blood Cells and Targeted Drug Delivery

J. Controll. Release 2024, 370, 302-309.

6 Zhang, H.; Yan, W.; Wang, J.; Xie, S.; Tao, W. A.; Lee, C.-W.; Zhang, X.; Zhang, G.; Liu, Y.; Wei, D.; Hu, J.; Liu, H.; Liu, F.; Nie, Y.; Chen, X.; Xu, H.*; Xia, J.*; Wang, S.*

Surface functionalization of exosomes for chondrocyte-targeted siRNA delivery and cartilage regeneration

J. Controll. Release 2024, 369, 493-505.

7 Han, Y.; Jiang, H.; Huang, C.; Wu, X.; Ouyang, Y.; Chen, H.; Lan, D.; Wang, Y.; Zheng, B.; Xia, J.*

Enzymatic Interfacial Conversion of Acylglycerols in Pickering Emulsions Stabilized by Hydrogel Microparticles

J. Colloid Interface Sci. 2024, 661, 228-236.

/